OpenAIRE Guidelines for Data Archive Managers v1.0

OpenAIRE gathers together research output related to European funding streams, with the aim of supporting open science and tracking research impact. This content consists of open access publications and related contextual information such as datasets, supplementary material, and research/project information. Two other sets of OpenAIRE guidelines exist for repository managers: OpenAIRE Guidelines for Literature Repositories 3.0 OpenAIRE Guidelines for CRIS systems (CERIF standard) – In draft The OpenAIRE Guidelines for Data Archive Managers 1.0 provides instruction for data archive managers to expose their metadata in a way that is compatible with the OpenAIRE infrastructure. The metadata from data archives should be included in the OpenAIRE information space, and exposed when data are related to an open access publication e.g. a dataset cited by an article. By implementing the OpenAIRE Guidelines data archive managers are facilitating the creation of enhanced publications and building the stepping-stones for a linked data infrastructure for research. Exposure and visibility of content from a range of European repositories will be significantly increased when a common and interoperable approach is taken and care to adhere to existing guidelines. OpenAIRE is happy to assist in adherence to these guidelines. This compatibility will lead to future interoperability between research infrastructures, and structured metadata is of benefit to individual data repositories and the scholarly community at large

OpenAIRE guidelines: supporting interoperability for Data Archives

OpenAIRE supports the European Commission Open Access policy by providing an infrastructure for researchers to comply with the European Union Open Access mandate. The current OpenAIRE infrastructure and services, resulting from OpenAIRE and OpenAIREplus FP7 projects, builds on Open Access research results from a wide range of repositories and other data sources: institutional or thematic publication repositories, Open Access journals, data repositories, Current Research Information Systems and aggregators. (...

Mild Skin Heating Evokes Warmth Hyperknesis Selectively for Histaminergic and Serotoninergic Itch in Humans

Chronic itch can severely affect quality of life. Patients report that their chronic itch can be exacerbated by exposure to warm conditions (“warmth hyperknesis”). The aim of this mechanistic study was to investigate the effect of mild heating of the skin in humans on various experimental models of itch. A total of 18 healthy subjects were recruited to the study. Itch was provoked by histamine, serotonin, or cowhage in 3 different sessions. The provoked area was heated with an infrared lamp, and the skin temperature was either not altered, or was increased by 4°C or 7°C. Subsequent to induction of itch, the itch intensity was recorded for 10 min while the skin was heated continuously throughout the entire period of itch induction. Heating the skin resulted in a significant increase in itch intensity when provoked by histamine or serotonin. It is possible that thermoception and pruriception interact and selectively produce a higher itch intensity in histaminergic and serotoninergic itch